Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives.

نویسندگان

  • Aaron Chen
  • Deborah K Lieu
  • Lauren Freschauf
  • Valerie Lew
  • Himanshu Sharma
  • Jiaxian Wang
  • Diep Nguyen
  • Ioannis Karakikes
  • Roger J Hajjar
  • Ajay Gopinathan
  • Elliot Botvinick
  • Charless C Fowlkes
  • Ronald A Li
  • Michelle Khine
چکیده

A biomimetic substrate for cell-culture is fabricated by plasma treatment of a prestressed thermoplastic shrink film to create tunable multiscaled alignment "wrinkles". Using this substrate, the functional alignment of human embryonic stem cell derived cardiomyocytes is demonstrated.

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منابع مشابه

Multiscale Wrinkles for Functional Alignment of Human Embryonic Stem Cells and their Cardiac Derivatives

www.MaterialsViews.com C O M M U N IC A IO N Aaron Chen , Deborah K. Lieu , Lauren Freschauf , Valerie Lew , Himanshu Sharma , Jiaxian Wang , Diep Nguyen , Ioannis Karakikes , Roger J. Hajjar , Ajay Gopinathan , Elliot Botvinick , Charless C. Fowlkes , Ronald A. Li , * and Michelle Khine * Shrink-Film Confi gurable Multiscale Wrinkles for Functional Alignment of Human Embryonic Stem Cells and t...

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عنوان ژورنال:
  • Advanced materials

دوره 23 48  شماره 

صفحات  -

تاریخ انتشار 2011